Delta-Sleep-Inducing Peptide (DSIP) | Laboratory Research Reagent
Product Specifications
- Peptide class: Linear nonapeptide.
- Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu.
- Molecular weight: Approximately 849 Da.
- Purity: ≥99%, HPLC verified.
- Laboratory solvent context: Aqueous diluent or PBS.
- Storage: −20 °C, protected from light and moisture.
For laboratory research use only. Not for use in humans or animals.
Identity and Research Scope
DSIP is a naturally occurring nonapeptide described in sleep-biology and neuroendocrine research. Its genetic origin and receptor interactions are described as incompletely understood, making pathway identification and experimental controls relevant to assay interpretation.
The peptide is described as amphiphilic. Solvent interactions and structural stability provide analytical research questions that should be evaluated under the selected laboratory conditions.
Neurochemical and Endocrine Assay Context
The listed literature discusses GABA, serotonin, and norepinephrine signaling measurements, together with ACTH, growth hormone, luteinizing hormone, and somatostatin readouts. These endpoints provide context for investigating neuroendocrine signaling, stress responses, energy regulation, and circadian timing.
Slow-wave and REM-associated observations vary across experimental models. Such findings provide literature context and do not establish a sleep-related outcome for the supplied laboratory material.
Laboratory Research Applications
- Slow-wave and circadian-signaling measurements.
- Neurotransmitter and hormone-associated assay readouts.
- Stress-response and thermoregulation pathway research.
- Oxidative and inflammatory signaling measurements.
- Peptide stability and aqueous solvent-interaction assays.
Analytical Material Information
The listed material has ≥99% HPLC-verified purity. Review analytical documentation when assessing material suitability and potential impurities. Experimental reproducibility depends on assay design, model conditions, and controls as well as reagent characterization.
Selected Research Context
The original bibliography attributes neuroendocrine research to De Wied, slow-wave measurements to Graf et al., circadian-timing research to Szentirmai, and model-dependent REM and delta observations to Vogel. These topics are presented as laboratory literature context.
Storage and Laboratory Handling
- Store at −20 °C in a tightly sealed container.
- Protect from light and moisture.
- Limit repeated freezing and thawing when managing laboratory aliquots.
- Select an aqueous diluent or PBS according to the analytical method and evaluate compatibility and stability under the specific assay conditions.
Chemical Structure

DSIP nonapeptide structure showing peptide bonds and amino-acid side chains.
Sequence Illustration

H–Trp–Ala–Gly–Gly–Asp–Ala–Ser–Gly–Glu–OH, with a free N-terminus and C-terminal carboxyl group.
Frequently Asked Questions
What laboratory research context is described for DSIP?
DSIP is discussed in slow-wave and circadian signaling research, neurotransmitter measurements, and neuroendocrine pathway studies. Experimental observations depend on the model and assay conditions.
What is the intended use of the supplied material?
DSIP is supplied as a laboratory research reagent for analytical characterization and research assays. For laboratory research use only. Not for use in humans or animals.
What is the peptide sequence and listed molecular weight?
DSIP is a linear nonapeptide with sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. The listed molecular weight is approximately 849 Da. The sequence illustration shows a free N-terminus and C-terminal carboxyl group.
What purity information is listed?
The listed purity is at least 99%, HPLC verified. Purity documentation helps researchers assess the material and potential impurities when designing assay controls; it does not establish experimental outcomes.
Which pathway questions remain under investigation?
The page describes DSIP receptor interactions and genetic origin as incompletely understood. Research contexts include GABA, serotonin, norepinephrine, ACTH, growth hormone, luteinizing hormone, and somatostatin measurements, alongside oxidative and inflammatory signaling endpoints.
For laboratory research use only. Not for use in humans or animals.




