LIPO-C Multi-Component Laboratory Research Complex
L-Carnitine (200 mg) + L-Methionine (25 mg) + Myo-Inositol (50 mg) + Choline Chloride (50 mg) + Cyanocobalamin (1 mg)
For laboratory research use only. Not for use in humans or animals.
TECHNICAL SPECIFICATIONS
| Property | Data |
|---|---|
| Product Reference | Lipo-C Multi-Component Lipotropic Research Reagent |
| Chemical Class | Multi-component biochemical laboratory reagent blend |
| Physical Format | Lyophilized powder in a hermetically sealed laboratory container |
| Net Reagent Content | 326 mass units total lyophilized content |
| Reagent Fraction 1 | L-Carnitine |
| CAS Registry | 541-15-1 |
| PubChem CID | 10917 |
| Molecular Formula | C7H15NO3 |
| Fraction Content | 200 mass units |
| Reagent Fraction 2 | L-Methionine |
| CAS Registry | 63-68-3 |
| PubChem CID | 6137 |
| Molecular Formula | C5H11NO2S |
| Fraction Content | 25 mass units |
| Reagent Fraction 3 | Myo-Inositol |
| CAS Registry | 87-89-8 |
| PubChem CID | 892 |
| Molecular Formula | C6H12O6 |
| Fraction Content | 50 mass units |
| Reagent Fraction 4 | Choline Chloride |
| CAS Registry | 67-48-1 |
| PubChem CID | 6145 |
| Molecular Formula | C5H14ClNO |
| Fraction Content | 50 mass units |
| Reagent Fraction 5 | Cyanocobalamin (Vitamin B12) |
| CAS Registry | 68-19-9 |
| PubChem CID | 5311498 |
| Molecular Formula | C63H88CoN14O14P |
| Fraction Content | 1 mass unit |
| Analytical Purity | ≥99% (RP-HPLC – per fraction) |
| Identity Confirmation | LC-MS – All five fractions verified |
| Endotoxin Screening | <0.25 EU (LAL method) |
| Laboratory Solvent System | Aqueous laboratory buffer / Solution |
| Storage – Lyophilized | 2–8°C, desiccated, light-protected |
| Storage – After Solubilization | -20°C, single-use aliquots advised |
| Research Classification | Research Use Only (RUO) |
Product Overview
LIPO-C is a lyophilized, five-component biochemical research reagent with a listed total content of 326 mg. Its component research contexts include mitochondrial fatty-acid transport, transmethylation, phospholipid biosynthesis, hepatic lipid transport, and cobalamin-dependent enzyme pathways.
The listed composition provides a defined starting point for multi-component laboratory assays. Individual-component literature does not establish additive effects, simultaneous pathway activity, or reproducible responses for the combined formulation. Evaluate material composition, assay compatibility, and analytical controls for the selected experimental system.
MOLECULAR STRUCTURE AND COMPONENT RESEARCH
Component 1: L-Carnitine, PubChem CID 10917
L-Carnitine is a quaternary ammonium compound with formula C7H15NO3. The carnitine palmitoyltransferase (CPT-I/CPT-II) shuttle provides research context for long-chain fatty-acid transport and mitochondrial beta-oxidation. Laboratory endpoints include fatty-acid flux and CPT enzyme kinetics in cell-based metabolic assays.
The retained image depicts choline chloride. It does not depict L-Carnitine. L-Carnitine PubChem structure reference.
Component 2: L-Methionine, PubChem CID 6137
L-Methionine is a sulfur-containing amino acid with formula C5H11NO2S. Methionine adenosyltransferase (MAT) catalyses its ATP-dependent conversion to S-adenosylmethionine (SAMe), providing a methyl-group donor for DNA, histone, and phospholipid methylation. Laboratory research includes transmethylation, DNMT-associated measurements, homocysteine metabolism, and glutathione precursor analysis. L-Methionine PubChem structure reference.
Component 3: Myo-Inositol, PubChem CID 892
Myo-Inositol is a carbocyclic polyol with formula C6H12O6 and provides the backbone for phosphatidylinositol (PI). PI derivatives including PIP2 and PIP3 provide research context for PI3K/Akt signaling and IP3-mediated calcium measurements. Assays may examine phospholipid turnover and second-messenger signaling in cellular metabolic systems. Myo-Inositol PubChem structure reference.
Component 4: Choline Chloride, PubChem CID 6145
Choline is a quaternary ammonium cation, C5H14NO, supplied here as choline chloride, C5H14ClNO. The CDP-choline (Kennedy) pathway provides context for phosphatidylcholine (PC) biosynthesis. PC is associated with membrane phospholipids and VLDL assembly. Laboratory endpoints include Kennedy-pathway flux, VLDL secretion, hepatic triglyceride measurements, and acetylcholine or betaine pathway studies. Choline Chloride PubChem structure reference.
Component 5: Cyanocobalamin (Vitamin B12), PubChem CID 5311498
Cyanocobalamin is a cobalt-containing corrinoid with formula C63H88CoN14O14P. Its relationship to methylcobalamin and 5’-deoxyadenosylcobalamin provides context for methionine synthase (MTR) and methylmalonyl-CoA mutase (MUT) enzyme research. Laboratory endpoints include homocysteine remethylation, methylmalonic-acid measurements, one-carbon transfer, and pathways associated with odd-chain fatty-acid and branched-chain amino-acid catabolism. Cyanocobalamin PubChem structure reference.
Research Mechanisms and Laboratory Assays
- Mitochondrial Fatty-Acid Transport: CPT-I/CPT-II kinetics and beta-oxidation flux in controlled cell-culture assays.
- Transmethylation: MAT activity, SAMe-associated methylation, and homocysteine pathway measurements.
- Phospholipid Signaling: PI turnover, PI3K/Akt signaling, and IP3-mediated calcium readouts.
- Hepatic Lipid Transport: Kennedy-pathway flux, VLDL assembly, and triglyceride measurements in hepatocyte and HepG2 systems.
- Cobalamin-Dependent Enzyme Research: MTR and MUT assay contexts involving one-carbon metabolism and propionate-related pathways.
Component Composition and Assay Context
| Component | Listed Content | Laboratory Research Context |
|---|---|---|
| L-Carnitine | 200 mg | Carnitine shuttle and beta-oxidation assays |
| L-Methionine | 25 mg | SAMe and transmethylation assays |
| Myo-Inositol | 50 mg | Phosphoinositide signaling assays |
| Choline Chloride | 50 mg | Kennedy pathway and VLDL assays |
| Cyanocobalamin | 1 mg | Cobalamin-dependent enzyme research |
The listed mass ratio is 200:25:50:50:1. This describes formulation composition; it does not establish the activity or saturation of any pathway under a particular assay condition.
WHY SOURCE FROM PROFOUND AMINOS
Five-Component Analytical Documentation
Profound Aminos lists per-component RP-HPLC purity testing and LC-MS identity confirmation for all five fractions. The batch COA provides composition, analytical results, lot number, and manufacturing date for laboratory material assessment.
Single-Batch Formulation
The listed 326 mg format combines the five components at a fixed mass ratio in a single lyophilization run. Assess homogeneity and component concentrations for the chosen solvent system and assay. Formulation ratio alone does not guarantee identical aliquots or experimental reproducibility.
USA Domestic Cold-Chain Shipping
Profound Aminos lists USA domestic shipping through monitored cold-chain materials handling from a climate-controlled facility. Storage and transport conditions are relevant to reagent stability and should be considered alongside the batch documentation.
RESEARCH USE AND LABORATORY HANDLING
For laboratory research use only. Not for use in humans or animals.
Use appropriate gloves, a lab coat, and protective eyewear during solubilization and handling. Consult the SDS for each component: L-Carnitine, CAS 541-15-1; L-Methionine, CAS 63-68-3; Myo-Inositol, CAS 87-89-8; Choline Chloride, CAS 67-48-1; and Cyanocobalamin, CAS 68-19-9.
Store lyophilized material at 2–8°C, desiccated and protected from light. After solubilization, store at −20°C in single-use aliquots, limit repeated freezing and thawing, and protect from light. Assess compatibility and stability in the selected aqueous laboratory buffer.
Frequently Asked Questions
What is the intended use of LIPO-C?
For laboratory research use only. Not for use in humans or animals.
What does the 326 mg format mean?
The listed total lyophilized content is 326 mg: L-Carnitine 200 mg, L-Methionine 25 mg, Myo-Inositol 50 mg, Choline Chloride 50 mg, and Cyanocobalamin 1 mg.
What solvent systems are listed for laboratory solubilization?
The existing handling information lists Solution or an aqueous PBS laboratory buffer. Assess solvent compatibility and select component-specific assay concentrations using the batch composition and experimental method.
How is solubilized LIPO-C stored?
Store at −20°C in single-use laboratory aliquots. Limit repeated freezing and thawing and protect the solution from light, particularly when evaluating cyanocobalamin stability.
Which components provide the biochemical research contexts?
L-Carnitine provides carnitine-shuttle context; L-Methionine provides transmethylation context; Myo-Inositol provides phosphoinositide-signaling context; Choline Chloride provides Kennedy-pathway context; and Cyanocobalamin provides cobalamin-cofactor context.
What research classification applies to the blend?
LIPO-C is supplied as a Research Use Only laboratory reagent for biochemical assays and analytical characterization.
How should component-level literature be interpreted?
Research on an individual component does not establish the properties or combined effects of the LIPO-C formulation. Interpret findings according to the compound identity, experimental model, concentrations, and assay conditions studied.
What laboratory safety information is relevant?
Use suitable gloves, a lab coat, and protective eyewear during solubilization and handling. Consult the SDS for each component and follow institutional laboratory safety procedures.
Do you provide a COA for every batch?
Yes. Batch COA documentation includes per-component RP-HPLC purity, LC-MS identity information for all five fractions, endotoxin screening, lot number, and manufacturing date. The page lists an endotoxin threshold below 0.25 EU in the specifications and below 0.25 EU/mg in the original COA description; confirm the applicable units and lot result in the batch COA.
What does the component mass ratio describe?
The listed formulation mass ratio is 200:25:50:50:1 for L-Carnitine, L-Methionine, Myo-Inositol, Choline Chloride, and Cyanocobalamin. This ratio describes material composition and does not establish saturation, assay suitability, or combined effects.
KEY REFERENCE IDENTIFIERS
The existing component bibliography lists Bremer J., Physiol Rev 1983;63:1420–1480; Flanagan JL et al., Nutr Metab 2010;7:30 (PMC2861661); Zeisel SH and da Costa KA, J Am Coll Nutr 2000;19(suppl):528S (PMID 11023003); Li Z and Bhalla V, Adv Nutr 2024; Unger RH and Orci L, Biochim Biophys Acta 2002;1585:202; Croze ML and Soulage CO (2013), PMID 23278466; and Green R et al., Nat Rev Dis Primers 2017;3:17040. Consult the original records for the component identities, models, and endpoints studied.
For laboratory research use only. Not for use in humans or animals.
