MOTS-c | Mitochondrial-Derived Laboratory Research Peptide
Product Specifications
- Length: 16 amino acids
- Molecular weight: ~1.7 kDa
- Purity: ≥99%, HPLC verified
- Listed solvent systems: Solution or PBS
- Storage: −20°C, protected from light and moisture
For laboratory research use only. Not for use in humans or animals.
Description
Origin and Mitochondrial Signaling
MOTS-c is a mitochondrial-derived peptide described as encoded in the 12S rRNA region of mitochondrial DNA. Its molecular origin provides laboratory research context for mitochondrial communication, cellular energy sensing, and metabolic pathway measurements.
Mito-Nuclear Communication
Laboratory research examines intracellular localization, nuclear-associated peptide measurements, and gene-expression changes under metabolic stress. Relevant readouts include antioxidant-response markers and cellular signaling. Transport mechanisms and direct molecular targets remain experimental questions.
Metabolic Pathway Assays
Glucose uptake, fatty-acid oxidation, AMPK-associated signaling, and lipid-metabolism measurements provide assay contexts. Evaluate these endpoints in defined cell systems with appropriate substrate conditions, concentrations, and analytical controls.
Longitudinal and Stress-Response Measurements
Research contexts include peptide abundance across sampling conditions, nutrient-deprivation responses, inflammatory signaling, and oxidative-stress markers. Model-dependent changes do not establish a general metabolic outcome for the supplied material.
Related Mitochondrial Peptides
MOTS-c, humanin, and SHLPs provide distinct contexts for mitochondrial peptide research. Assays may examine their molecular identities, localization, stability, and pathway interactions. Combined effects require evaluation within the selected experimental system.
Features / Highlights
- Mitochondrial-derived peptide with a listed 16-amino-acid length
- Glucose, lipid, and cellular stress assay context
- AMPK and mitochondrial signaling measurements
- Listed purity ≥99%, HPLC verified
Existing Literature Context
The existing bibliography lists Lee et al., Reynolds and Kim, Xu, Patel, Ross and Tanaka, Olson, Santos et al., Griffin, Jensen, and Miller for mitochondrial peptide, metabolic, and cellular signaling research. Consult original records for the exact materials and experimental models studied.
Storage Instructions
- Store at −20°C
- Keep sealed and protected from light and moisture
- Limit repeated freezing and thawing
Chemical Structure
FAQs
What is MOTS-c used for in laboratory research?
Research contexts include glucose metabolism, lipid oxidation, mitochondrial signaling, AMPK-associated pathways, and cellular metabolic stress responses.
What is the molecular origin of MOTS-c?
MOTS-c is described as a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA.
What is the intended use of the material?
For laboratory research use only. Not for use in humans or animals.
What measurements are relevant to longitudinal studies?
Laboratory studies may measure MOTS-c abundance, mitochondrial signaling, gene expression, and cellular stress markers across defined sampling conditions. Interpret changes within the specific experimental model.
Why is analytical purity relevant?
The listed purity is ≥99%, HPLC verified. Purity and identity data inform material assessment, but do not guarantee experimental reproducibility.
For laboratory research use only. Not for use in humans or animals.
